Worldwide, about 3 billion kg of pesticides is applied to cropland each year at a cost of about 45 billion per year and although insecticides are designed to attack weeds (herbicides), insect pests (insecticide), crop fungus (fungicide) they also affect nontarget species including humans.

For humans, pesticides are allergens, poisonings, and carcinogens, they cause irritation of the skin or eyes, coughing lacrimation. Poisoning with systemic effects, worldwide, the application of 3 million metric tons of pesticides results in more than 26 million cases of nonfatal poisoning and  About 90% of all fungicides are carcinogenic and studies shown that exposure to certain pesticides significantly increases the risk of cancer.

Pesticides are also dangerous to animals, frogs are increasingly exposed to pesticides in ponds and in the bodies of insects that they eat, this can make them more vulnerable to bacterial, viral and fungal diseases, and according to the U.S fish and wildlife service, pesticides kill about one-fifth of the European honey bee and here I mention that organic honey in Cuba becomes a key agricultural export since Cuba was unable to afford pesticides due to a lack of foreign exchange before 1991.Certain pesticides end up in groundwater and cause its contamination and they are washed also into aquatic systems causing fishery loss.

A study of evaluation of pesticides residues in fruits and vegetables from Algeria shows that 57.5% of fruits and vegetables samples collected from Algerian markets contained at least 1 pesticide residue.