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How Diclofenac can kill Vulture ? |
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by Deepak Subedi | 22-11-2018 22:38
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As a student of Veterinary Science and Animal Husbandry, it is my responsibility to share about toxic effect of Diclofenac to vulture to all ambassador, mentors and members. Diclofenac is a common anti-inflammatory drug administered to livestock and is used to treat the symptoms of inflammation, fevers and/or pain associated with disease or wounds. In Asia the drug is widely given to cattle because it is cheap and because losing livestock to lameness or fever can be devastating to small farmers with only a few animals. The primary mechanism responsible for its anti-inflammatory, antipyretic, an analgesic action is thought to be inhibition of prostaglandin synthesis by inhibition of cycloxygenase-2 (COX-2). Diclofenac inhibits COX-2 with 20-fold more potency than COX-1 and is said to have a lower incidence of gastrointestinal complaints than COX-1 inhibitors such as aspirin. Diclofenac is given to working and ill farm cattle to reduce pain so that they can work on the land for longer. Farmers leave dead farm animals out in the open for the vultures to tidy up, and the vultures then feed from the carcasses of the cattle that die, and are poisoned by the Diclofenac contained in the flesh they eat. After eating flesh of dead animals which contain Diclofenac vulture suffer from visceral gout. Visceral gout is a disease of birds in which kidney failure causes a build-up of urates in the internal organs, leaving a chalky white coating on them. Symptoms include anorexia and emaciation. Vultures are particularly sensitive to poisoning by Diclofenac, which leads to renal failure, visceral gout and death to them. Nepal had banned the use of the drug that proved toxic for vultures some 12 years ago, following a dramatic fall in the number of scavenging birds from Nepal, India, Bangladesh and Pakistan. As per the Drugs Act-1978, anyone found producing, using, selling, importing, exporting and storing this drug, shall face three years jail term or a fine of Rs 25,000 cash or both. Meloxicam (another NSAID) has been found to be harmless to vultures and should prove an acceptable alternative to Diclofenac. Regardless of family, all vultures play a significant role in keeping our ecosystem healthy and clean. Vultures do not hunt live prey, but act as scavengers feeding on the carcasses of dead animals. The acid in their stomachs is highly corrosive, facilitating the digestion of decomposing carcasses infected with diseases such as anthrax, cholera, botulinum toxin, and rabies that would be lethal to other scavengers. Despite first impressions, vultures are actually very hygienic animals. Featherless or lightly feathered heads and necks help to keep vultures clean as they feed. #SaveVultures #StopDiclofenaceUse Source : Google http://www.birdlifenepal.org/news |
   
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12 Comments
Greetings Deepak
I hope you are doing well!
Thank you so much for this report!
Keep writing
Green cheers
Regards
Hema
Posted 22-03-2020 11:09
Greetings deepak
I hope you are doing well
Thank you so much for this report.
I hope to read more from you.
Keep up with great works
Green cheers
Regards
Basanta
Posted 16-03-2020 04:06
Hello Joon Ho Mentor, Namaste
Welcome
Thank you for searching about diclofenac and writing comments in my report.
such many farmers are still unaware about this and they are using diclofenac and local vet practitioner may lack knowledge. Awareness and education is necessary.
Posted 26-11-2018 18:12
Wow, lots of feedbacks up here :)
Hello Deepak, I just searched diclofenac on the Internet and this anti-inflammatory drug for cattle affects birds a lot, especially the ones that eat dead cattle or meat of them.
Such phenomena and food chain effect coming from toxication or chemical compound usage were allegedly known in the book 'Silent Spring' of Rachel Carson in 1960s.
However, such happening still does exist till now as we are not aware of it.
Thanks for introducing diclofenac and its effect to us!
Posted 25-11-2018 22:25
Hello Asmita Baini
The main Pathognomonic lesion due to adverse effect of Diclofenac in Vulture is Visceral Gout, other symptoms vary accordingly,
Thank you for your comments :)
Posted 24-11-2018 13:44
Acute diclofenac overdosage produces manifestations that are mainly extension of adverse effects of the drug. Loss of consciousness, increased intracranial pressure, and aspiration pneumonitis were reported in a 17 year old male who died 2 days after ingestion 5 g of diclofenac.
[American Society of Health-System Pharmacists 2011 Drug Information 2011. Bethesda, MD. 2011, p. 2112]
It has direct negative consequences to both human and ecosystem...
Thank you so much for information Deepak dai,
Posted 24-11-2018 13:10
Hello Sandhya Baini, Namaste
Thank you for reading this article and you are welcome.
Posted 23-11-2018 14:25
Hello Viraaj Kulshreshtha , Namaste
Thank you so much for reading this article and writing comments.
Posted 23-11-2018 14:24
Deepak Subedi says :
Hello Rosa didi, Namaste
Vulture are natural scavenger and they play very important role in ecosystem and helps to maintain the healthy environment by eating dead animals
Due to high dose use of diclofenace in cattle eagle population was decreasing but soon diclofenac was banned their population start increasing.
Thank you Rosa for your comments.
Posted 23-11-2018 14:23
Thank you deepak daai for sharing this information with us.
Posted 23-11-2018 11:26
Hi Deepak,
truly enlightened with your article.
Thanks
Posted 23-11-2018 03:51
Hey there Deepak :D
It's fascinating to just be informed about what you studying. And it's amazing that the Drugs Act-1978 is such a strict regulation against those who cross it.
Vultures are an important specie that should be protected. They play such a big role in being the decomposes of carcasses.
Thank you so much for inlightening us with your report!
Yours sincerely
R
Posted 23-11-2018 00:09